FIELD: chemistry.
SUBSTANCE: invention relates to 5-bromo-2-(thietan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one derivatives of general formula: , R=H(I a, c), CH3 (lb); n=0(I a, b), 2 (Ic).
EFFECT: disclosed compounds have antidepressant activity comparable with fluoxetine, while being less toxic and safer.
5 cl, 3 tbl, 6 ex
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Authors
Dates
2012-08-27—Published
2011-05-06—Filed