FIELD: chemistry.
SUBSTANCE: invention relates to pharmaceutical chemistry and pharmacology, namely to derivatives of N4-mono- and N2,N4-dithietane-containing 5-bromo-2,4-dihydro-1,2,4-triazol-3-one (compounds I-IV) of general formula: 
, where R=H, n=0, 1, 2 (I-III); 
n=1 (IV).
EFFECT: compounds I-IV have antidepressant activity.
6 cl, 2 tbl, 6 ex
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