FIELD: chemistry; pharmaceutics.
SUBSTANCE: invention refers to pharmaceutical chemistry and pharmacology, namely to derivatives of 5-amino-substituted 3-bromo-4-nitro-1- (thietan-3-yl)-1H-pyrazole (compounds I-V, VII) of general formula:
where NRR' is cyclohexylamino-1 (compound I), or benzylamino-1 (compound II), or pyrrolidino-1 (compound III), or piperidino-1 (compound IV), or piperazino-1 (compound V), or azepano-1 (compound VII).
EFFECT: compounds I-V, VII have antidepressant activity.
8 cl, 1 tbl, 8 ex
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