MEASURING AGGLUTINATION PARAMETERS Russian patent published in 2012 - IPC G01N15/02 

Abstract RU 2460058 C2

FIELD: physics.

SUBSTANCE: method and system for measuring agglutination in a target-induced agglutination assay with one or more magnetic particles, performed in a reaction chamber, are described. After the magnetic particles (3, 15), which are capable of binding to a target (5) are provided in the assay, an agglutination process is performed resulting in agglutinated particles (100) which contain at least one magnetic particle. The method further involves applying an alternating current magnetic field (HPT) to the assay and measuring an effect of the HPT on one or more magnetic particles (3, 15) unattached to any surface. The measured effect indicates one or more agglutination parameters.

EFFECT: high accuracy, ensuring high efficiency and sensitivity during quantitative measurement of one or more agglutination parameters of magnetic labels in a target-induced agglutination assay.

16 cl, 21 dwg

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RU 2 460 058 C2

Authors

Dittmer Uehndi U.

De Kivit Peggi

Nievenejs Jerun Kh.

Prins Menno V. J.

Van Ehjzendorn Leonardus J.

Janssen Ksander J. A.

Dates

2012-08-27Published

2007-12-18Filed