FIELD: physics.
SUBSTANCE: input light beam (L1) is transmitted to a carrier (11) where there is frustrated total internal reflection (FTIR) on the binding surface (12). The amount of light in the resultant output light beam (L2) is detected by an optical detector (31) and gives information on the presence of target particles on the binding surface. An actuating unit (50) induces rotation of bound target particles (1) by interacting with a magnetic field (B) or an electric field, with modulation frequency (ωm), from the condition that, by demodulating the signal (S) of the detector, effects of target particles differ from the background.
EFFECT: high accuracy and sensitivity of detection.
23 cl, 6 dwg
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Authors
Dates
2013-08-10—Published
2008-10-31—Filed