2-AZA-BICYCLO[3,1,0]HEXANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS Russian patent published in 2012 - IPC C07D417/14 A61K31/427 A61P25/00 

FIELD: chemistry.

SUBSTANCE: invention relates to novel 2-aza-bicyclo[3,1,0]hexane derivatives of formula (I), where A, B, n and R¹ are defined in the description, and to use of such compounds or pharmaceutically acceptable salts of such compounds as medicinal agents, particularly as orexin receptor antagonists. The present invention also describes use of compounds of general formula (I) to produce a medicinal agent for preventing or treating insomnia.

EFFECT: improved method.

11 cl, 279 ex, 1 tbl, 10 dwg