TREATMENT OF HYDRADENITIS WITH JAK INHIBITORS Russian patent published in 2023 - IPC A61K31/4985 A61K31/506 A61K31/519 A61P17/00 

Abstract RU 2805595 C1

FIELD: medicine.

SUBSTANCE: invention relates to a method of treating hidradenitis suppurativa. A proposed method of treating hidradenitis suppurativa (HS) in a subject having lesions associated with hidradenitis suppurativa comprises the step of administering to the subject in need thereof the following compound [(1S)-2,2-difluorocyclopropyl][(1R,5S)-3-{2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrimidin-4-yl}-3,8-diazabicyclo[3.2.1]oct-8-yl]methanone, which specifically inhibits Tyk2/JAK1, or its pharmaceutically acceptable salt.

EFFECT: use of the invention provides effective, safe and well-tolerated treatment for patients with moderate to severe HS.

7 cl, 8 ex

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RU 2 805 595 C1

Authors

Fensome, Andrew

Gerstenberger, Brian Stephen

Owen, Dafydd Rhys

Dates

2023-10-20Published

2020-09-08Filed