DIAGNOSTIC TECHNIQUE FOR HYPERANDROGENISM SYNDROME IN WOMEN OF REPRODUCTIVE AGE Russian patent published in 2012 - IPC A61B5/107 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, particularly endocrinology and gynaecology. Diagnosing of hyperandrogenism syndrome in women of reproductive age is enabled by objective, laboratory and instrumental examintation. At the first stage, a combination of clinical manifestations in the patients are grouped. The second stage of the diagnosing involves the patients having clinical manifestations of hyperandrogenism if observing at least two indicators of the various clinical groups. At the second stage, the levels of prolactin, total testosterone, globulin-binding sex steroids (GBSS) are measured. It is followed by calculating a free androgen index (FAI) by formula FAI = total testosteron/GBSS × 100%. The third stage of diagnosing involves the patients with diagnosed hyperandrogenism syndrome on the basis of the level of total testosteron and/or FAI > 2%. At the third stage of diagnosing, blood lipid profile, immunoreactive insulin (IRI), blood glucose on an empty stomach are evaluated. The index HOMA=(glucose mole/l × IRI mcUnit/ml)/22.5 and the index Caro=glucose mole/l/IRI are calculated with detecting metabolic complications of hyperandrogenism syndrome.

EFFECT: method enables diagnosing hyperandrogenism syndrome in women of reproductive age.

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