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(19)

(11)

2 461 543

(13)

(51)

IPC

C07C233/25(2006-01-01)

A61P29/00(2006-01-01)

C07C231/10(2006-01-01)

A61K31/167(2006-01-01)

(21) (22)

Application

2011123808/04, 2011-06-10

(24)

Start date

2011-06-10

(22)

Actual filing date

2011-06-10

(45)

Published

2012-09-20

(72)

Inventor

Azev Jurij AlekseevichCharushnikov Kirill AleksandrovichMokrushin Vladimir StepanovichGibor Aleksej Mikhajlovich

(73)

Holder

Federal'Noe Gosudarstvennoe Avtonomnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Federal'Nyj Universitet Imeni Pervogo Prezidenta Rossii B.N. El'Tsina"

METHOD FOR PRODUCING PARACETAMOL Russian patent published in 2012 - IPC C07C233/25 A61P29/00 C07C231/10 A61K31/167

Abstract RU 2461543 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: what is offered is a method for producing paracetamol consisting in n-nitrosophenol recovery in ethyl acetate in the presence of the Pd/C-containing catalyst at hydrogen pressure 2.0-4.0 atm and temperature 20-50°C that is followed by acylation of formed n-aminophenol and end product recovery.

EFFECT: simplified technology and higher end product yield.

1 cl, 4 ex

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RU 2 461 543 C1

Authors

Azev Jurij Alekseevich

Charushnikov Kirill Aleksandrovich

Mokrushin Vladimir Stepanovich

Gibor Aleksej Mikhajlovich

Dates

2012-09-20—Published

2011-06-10—Filed