FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing n-acetylaminophenol (paracetamol) of formula I . The method involves catalytic reduction of n-nitrosophenol in ethyl acetate while mixing with a Raney-Ni catalyst at hydrogen pressure of 2-4 atm at temperature of 20-50°C, followed by treatment of the obtained n-aminophenol with acetic anhydride and separating the end product.
EFFECT: improved method of producing n-acetylaminophenol.
2 dwg, 3ex
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Authors
Dates
2013-10-20—Published
2012-07-10—Filed