METHOD FOR PRODUCING PARACETAMOL Russian patent published in 2018 - IPC C07C231/24 C07C233/25 

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry, namely to a method for producing paracetamol (P-acetaminophenol). Method is carried out as follows: reactor is loaded with water and technical paracetamol, reaction mixture is heated to 85±5 °C, held for 10-20 minutes, filtered through the druckfilter into the crystallizer, then the reaction mass is self-cooled for 2.5 hours, after which it is further cooled to a temperature of 15±5 °C and held for 1.5-3.0 hours. Further, the reaction mixture is filtered, washed with purified water, then it is dried at a temperature of 90±5 °C to a moisture content of not more than 0.5%.

EFFECT: invention provides the possibility of obtaining paracetamol of compendial grade and increase in the yield of the finished product.

3 cl, 2 ex