FIELD: medicine.
SUBSTANCE: Aspergillus ochraceus strain is recovered from plant residue samples on wort agar and deposited in Russian National Collection of Microorganisms, No. F-4105D. The strain produces proteinase being a human blood plasma protein C activator into a culture fluid while grown on a medium containing carbohydrate and protein compounds, and mineral salts. Anticoagulant activity of the strain to prolong activated partial thromboplastin time by 2 cultivation days makes 920%. Proteinase activity of the strain Aspergillus ochraceus in the culture fluid determined with the use of chromogenic peptide substrate pGlu-Pro-Arg-pNA makes 72.5 units/ml.
EFFECT: higher proteinase activity of the strain.
1 tbl, 2 ex
Title | Year | Author | Number |
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STRAIN ASPERGILLUS OCHRACEUS - HUMAN BLOOD PLASMA PROTEIN C ACTIVATOR PROTEINASE PRODUCER | 2011 |
|
RU2461614C2 |
STRAIN ASPERGILLUS OCHRACEUS - HUMAN BLOOD PLASMA PROTEIN C ACTIVATOR PROTEINASE PRODUCER | 2011 |
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Authors
Dates
2012-09-20—Published
2011-03-09—Filed