STRAIN ASPERGILLUS OCHRACEUS - HUMAN BLOOD PLASMA PROTEIN C ACTIVATOR PROTEINASE PRODUCER Russian patent published in 2012 - IPC C12N1/14 C12N9/62 C12R1/66 

Abstract RU 2461615 C2

FIELD: medicine.

SUBSTANCE: Aspergillus ochraceus strain is recovered from plant residue samples on wort agar and deposited in Russian National Collection of Microorganisms, No. F-4105D. The strain produces proteinase being a human blood plasma protein C activator into a culture fluid while grown on a medium containing carbohydrate and protein compounds, and mineral salts. Anticoagulant activity of the strain to prolong activated partial thromboplastin time by 2 cultivation days makes 920%. Proteinase activity of the strain Aspergillus ochraceus in the culture fluid determined with the use of chromogenic peptide substrate pGlu-Pro-Arg-pNA makes 72.5 units/ml.

EFFECT: higher proteinase activity of the strain.

1 tbl, 2 ex

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Authors

Kurakov Aleksandr Vasil'Evich

Osmolovskij Aleksandr Andreevich

Krejer Valeriana Georgievna

Baranova Nina Andreevna

Egorov Nikolaj Sergeevich

Dates

2012-09-20Published

2011-03-09Filed