FIELD: biotechnologies.
SUBSTANCE: method for obtaining proteinase - protein C activator of blood plasma provides for solid-phase cultivation of fungus strain Aspergillus ochraceus BKM F-4104D on a substrate. The substrate contains the following components at a certain ratio: a solid substance or a carrier, glucose, amylum, hydrolysate of fish flour, peptone, NaCl, KH2PO4, MgSO4·7H2O, and water. As a solid substance or a carrier, vermiculite, polyurethane foam, silica gel or wheat middlings are used. Proteinase activity is up to 300 U/ml.
EFFECT: invention allows obtaining a target product with improved activity.
5 tbl, 15 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF OBTAINING PROTEINASE-ACTIVATOR OF PROTEIN C IN BLOOD PLASMA | 2011 |
|
RU2468081C2 |
| METHOD OF PRODUCING PROTEINASE - ACTIVATOR X OF FACTOR OF BLOOD PLASMA | 2017 |
|
RU2687344C1 |
| STRAIN ASPERGILLUS OCHRACEUS - HUMAN BLOOD PLASMA PROTEIN C ACTIVATOR PROTEINASE PRODUCER | 2011 |
|
RU2461614C2 |
| METHOD FOR OBTAINING PROTEINASE WITH FIBRINOLYTIC AND FIBRINOGENOLYTIC ACTIVITY | 2016 |
|
RU2664468C2 |
| STRAIN ASPERGILLUS OCHRACEUS - HUMAN BLOOD PLASMA PROTEIN C ACTIVATOR PROTEINASE PRODUCER | 2011 |
|
RU2460772C2 |
| STRAIN ASPERGILLUS OCHRACEUS - HUMAN BLOOD PLASMA PROTEIN C ACTIVATOR PROTEINASE PRODUCER | 2011 |
|
RU2461615C2 |
| STRAIN ASPERGILLUS OCHRACEUS - HUMAN BLOOD PLASMA PROTEIN C ACTIVATOR PROTEINASE PRODUCER | 2011 |
|
RU2461616C2 |
| STRAIN SAROCLADIUM STRICTUM - PRODUCER OF FIBRINOLYTIC ENZYMES WITH PLASMINOGEN ACTIVATING ACTIVITY | 2019 |
|
RU2728456C1 |
| ASPERGILLUS CLAVATUS STRAIN - PRODUCER OF PROTEOLITIC ENZYMES WITH KERATINOLYTIC ACTIVITY | 2021 |
|
RU2774366C1 |
| METHOD OF DETECTION OF INHIBITORS OF MICROBIAL STEROLS | 0 |
|
SU1813785A1 |
