STRAIN ASPERGILLUS OCHRACEUS - HUMAN BLOOD PLASMA PROTEIN C ACTIVATOR PROTEINASE PRODUCER Russian patent published in 2012 - IPC C12N1/14 C12N9/62 C12R1/66 

Abstract RU 2461616 C2

FIELD: medicine.

SUBSTANCE: Aspergillus ochraceus strain is recovered from carbonate chernozem samples and deposited in Russian National Collection of Microorganisms, No. F-4106D. The strain produces proteinase being a human blood plasma protein C activator into a culture fluid while grown on a medium containing carbohydrate and protein compounds, and mineral salts. Anticoagulant activity of the strain to prolong activated partial thromboplastin time by 2 cultivation days makes 960%. Proteinase activity of the strain Aspergillus ochraceus in the culture fluid determined with the use of chromogenic peptide substrate pGlu-Pro-Arg-pNA makes 77.9 units/ml.

EFFECT: higher proteinase activity of the strain.

1 tbl, 2 ex

Similar patents RU2461616C2

Title Year Author Number
STRAIN ASPERGILLUS OCHRACEUS - HUMAN BLOOD PLASMA PROTEIN C ACTIVATOR PROTEINASE PRODUCER 2011
  • Osmolovskij Aleksandr Andreevich
  • Kurakov Aleksandr Vasil'Evich
  • Krejer Valeriana Georgievna
  • Baranova Nina Andreevna
  • Egorov Nikolaj Sergeevich
RU2461614C2
METHOD OF OBTAINING PROTEINASE-ACTIVATOR OF PROTEIN C IN BLOOD PLASMA 2011
  • Osmolovskij Aleksandr Andreevich
  • Krejer Valeriana Georgievna
  • Baranova Nina Andreevna
  • Kurakov Aleksandr Vasil'Evich
  • Egorov Nikolaj Sergeevich
RU2468081C2
METHOD OF SOLID-PHASE CULTIVATION OF Aspergillus ochraceus TO OBTAIN PROTEINASE - PROTEIN C ACTIVATOR OF BLOOD PLASMA 2013
  • Osmolovskij Aleksandr Andreevich
  • Kurakov Aleksandr Vasil'Evich
  • Krejer Valeriana Georgievna
  • Baranova Nina Andreevna
  • Egorov Nikolaj Sergeevich
RU2535872C2
STRAIN ASPERGILLUS OCHRACEUS - HUMAN BLOOD PLASMA PROTEIN C ACTIVATOR PROTEINASE PRODUCER 2011
  • Kurakov Aleksandr Vasil'Evich
  • Osmolovskij Aleksandr Andreevich
  • Krejer Valeriana Georgievna
  • Baranova Nina Andreevna
  • Egorov Nikolaj Sergeevich
RU2461615C2
STRAIN ASPERGILLUS OCHRACEUS - HUMAN BLOOD PLASMA PROTEIN C ACTIVATOR PROTEINASE PRODUCER 2011
  • Osmolovskij Aleksandr Andreevich
  • Kurakov Aleksandr Vasil'Evich
  • Krejer Valeriana Georgievna
  • Baranova Nina Andreevna
  • Egorov Nikolaj Sergeevich
RU2460772C2
METHOD FOR OBTAINING PROTEINASE WITH FIBRINOLYTIC AND FIBRINOGENOLYTIC ACTIVITY 2016
  • Osmolovskij Aleksandr Andreevich
  • Kurakov Aleksandr Vasilevich
  • Krejer Valeriana Georgievna
  • Baranova Nina Andreevna
  • Egorov Nikolaj Sergeevich
RU2664468C2
METHOD OF PRODUCING PROTEINASE - ACTIVATOR X OF FACTOR OF BLOOD PLASMA 2017
  • Orekhova Anastasiya Vladimirovna
  • Osmolovskij Aleksandr Andreevich
  • Kurakov Aleksandr Vasilevich
  • Krejer Valeriana Georgievna
  • Baranova Nina Andreevna
RU2687344C1
STRAIN SAROCLADIUM STRICTUM - PRODUCER OF FIBRINOLYTIC ENZYMES WITH PLASMINOGEN ACTIVATING ACTIVITY 2019
  • Kornienko Elena Igorevna
  • Osmolovskij Aleksandr Andreevich
  • Sharkova Tamara Sergeevna
  • Nalobin Denis Sergeevich
  • Kurakov Aleksandr Vasilevich
RU2728456C1
METHOD OF DETECTION OF INHIBITORS OF MICROBIAL STEROLS 0
  • Egorov Nikolaj Sergeevich
  • Landau Ninel Solomonovna
  • Baranova Nina Andreevna
  • Krejer Valeriana Georgievna
  • Vybornykh Svetlana Nikolaevna
  • Buyak Lyudmila Iosifovna
SU1813785A1
METHOD FOR THE TREATMENT OF CATARRHAL MASTITIS IN COWS 2021
  • Shabunin Sergej Viktorovich
  • Vostroilova Galina Anatolevna
  • Klimov Nikolaj Timofeevich
  • Cheskidova Liliya Valerevna
  • Khokhlova Nina Alekseevna
  • Miroshnikov Konstantin Anatolevich
  • Osmolovskij Aleksandr Andreevich
  • Komarevtsev Sergej Konstantinovich
RU2768608C1

RU 2 461 616 C2

Authors

Kurakov Aleksandr Vasil'Evich

Osmolovskij Aleksandr Andreevich

Krejer Valeriana Georgievna

Baranova Nina Andreevna

Egorov Nikolaj Sergeevich

Dates

2012-09-20Published

2011-03-09Filed