PYRAZOLE DERIVATIVES AS 11-BETA-HSD1 INHIBITORS Russian patent published in 2012 - IPC C07D231/14 C07D231/18 C07D403/06 C07D405/12 A61K31/415 A61K31/4155 A61P3/00

Abstract RU 2462456 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a compound which is 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid or a pharmaceutically acceptable salt thereof. The invention also relates to use thereof to inhibit 11βHSD1 (11-β-hydroxysteroid-dehydrogenase type 1), synthesis method thereof and a pharmaceutical composition containing said compounds.

EFFECT: improved method.

12 cl, 1 tbl, 47 ex

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RU 2 462 456 C2

Authors

Paker Martin Dzhon

Skott Dzhejms Stjuart

Stoker Ehndrju

Uittamor Pol Robert Ouehn

Dates

2012-09-27—Published

2008-02-11—Filed