METHOD FOR ESTIMATING CLINICAL EFFECTIVENESS OF ISCHEMIC HEART DISEASE Russian patent published in 2012 - IPC G01N33/92 

FIELD: medicine.

SUBSTANCE: before and after treating ischemic heart disease, modified lipoproteins(a) are evaluated by processing blood serum 0.6 ml by 0.1% Triton X-100 0.2 ml, by incubation for 15 minutes at 20°C, agitating stirring of the mixture at 120 times per minutes, disintegration with added 7% polyethylene glycol 6000, incubation with the staining agent Sudan B at 40°C for 1 h that is followed by electrophoretic separation of lipoproteins in agarose gel in a well 4×20 mm. Treatment of ischemic heart disease is estimated to be effective if observing decrease of the level of modified lipoproteins(a) by 30% and more, and increase of blood high density lipoproteins up to 30% and more, HDLP cholesterol 0.8 to 1.6 mmole/l and more as compared with the initial level.

EFFECT: using the presented method enables higher accuracy of evaluating the clinical effectiveness in ischemic heart disease.

1 tbl, 3 ex, 6 dwg