METHOD FOR ESTIMATING CLINICAL EFFECTIVENESS OF ISCHEMIC HEART DISEASE Russian patent published in 2013 - IPC G01N33/49 

FIELD: medicine.

SUBSTANCE: pre- and post-therapeutic lipoprotein (a) (LP (a)) is determined by processing blood serum 0.3 ml in 0.1% Triton X-100 and incubation for 15 minutes at 20°C. The mixture is agitated at 120 times per minute, disintegrated; patient's blood serum is incubated with Sudan B for 1 h in a dark thermostat at 40°C. A sample is introduced into a well 4×20×10 mm in agarose gel; that is followed by fixation, drying and densitometry of the electrophoretograms. If observing a decrease of the LP (a) level by 30% and more as compared with an initial level and an increase of the HDL level by 30%, HDP cholesterol 0.8 to 1.6 mmole/l and more, treating ischemic heart disease is considered to be effective.

EFFECT: invention enables higher accuracy of estimating the clinical effectiveness in ischemic heart disease ensured by determining the LP (a) levels by the developed method, as well as the HDP and cholesterol levels before and after treatment.

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