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2 465 006

(13)

(51)

IPC

A61K39/00(2006-01-01)

(21) (22)

Application

2010114819/15, 2010-04-14

(24)

Start date

2010-04-14

(22)

Actual filing date

2010-04-14

(45)

Published

2012-10-27

(72)

Inventor

Gendon Jurij ZakharovichMarkushin Stanislav GeorgievichAkopova Irina IvanovnaKrivtsov Georgij GeorgievichPereverzev Aleksandr DimitrievichSukhno Anatolij Sergeevich

(73)

Holder

Uchrezhdenie Rossijskoj Akademii Meditsinskikh Nauk Nauchno-Issledovatel'Skij Institut Vaktsin I Syvorotok Im. I.I. Mechnikova Ramn Im. I.I. Mechnikova Ramn)

METHOD FOR IMPROVING IMMUNOGENICITY OF COLD-ADAPTED LIVE INFLUENZA VACCINE Russian patent published in 2012 - IPC A61K39/00

Abstract RU 2465006 C2

FIELD: medicine.

SUBSTANCE: invention refers to medical industry and concerns production of a live influenza xa vaccine. The method for improving immunogenicity of the cold-adapted influenza vaccine is characterised by the fact that the vaccine is added by an adjuvant presented by chitosonium glutamate of final concentration 0.5% having a degree of deacetylation within 66-99% and molecular weight within 70-500 kDa.

EFFECT: method is easy to implement and enables effectively improving immunogenicity of the cold-adapted influenza vaccine.

5 tbl, 5 ex

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RU 2 465 006 C2

Authors

Gendon Jurij Zakharovich

Markushin Stanislav Georgievich

Akopova Irina Ivanovna

Krivtsov Georgij Georgievich

Pereverzev Aleksandr Dimitrievich

Sukhno Anatolij Sergeevich

Dates

2012-10-27—Published

2010-04-14—Filed