Show metadata Hide metadata

(19)

(11)

2 556 833

(13)

(51)

IPC

C12N7/00(2006-01-01)

A61K39/145(2006-01-01)

(21) (22)

Application

2011128981/10, 2011-07-12

(24)

Start date

2011-07-12

(22)

Actual filing date

2011-07-12

(45)

Published

2015-07-20

(72)

Inventor

Isakova-Sivak Irina NikolaevnaRudenko Larisa Georgievna

(73)

Holder

Uchrezhdenie Rossijskoj Akademii Meditsinskikh Nauk Nauchno-Issledovatel'Skij Institut Ehksperimental'Noj Meditsiny Severo-Zapadnogo Otdelenija Ramn Szo Ramn)

ATTENUATED COLD-ADAPTED INFLUENZA VIRUS STRAIN A/PR/8/59/M2 (H1N1) APPLICABLE FOR VACCINAL INFLUENZA VIRUS STRAINS AS ATTENUATION DONOR, VACCINAL INFLUENZA VIRUS STRAINS A/59/M2/CALIFORNIA/66/2211 (H2N2) AND A/59/M2/TOKYO/67/22111 (H2N2) Russian patent published in 2015 - IPC C12N7/00 A61K39/145

Abstract RU 2556833 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: inventions concern the influenza virus strains A/PR/8/59/M2 (H1N1), A/California/1/66 (H2N2) and A/Tokyo/3/67 (H2N2). The vaccinal strains A/59/M2/California/66/2211 (H2N2) and A/59/M2/Tokyo/67/22111 (H2N2) are reassortants prepared by crossing epidemic viruses A/California/1/66 (H2N2) and A/Tokyo/3/67 (H2N2) with cold-adapted heat-sensitive virus A/PR/8/59/M2 (H1N1). The strains A/59/M2/California/66/2211 (H2N2) and A/59/M2/Tokyo/67/22111 (H2N2) are characterised by heat sensitivity, cold adaption, safety and immunogenicity for laboratory animals. The reassortants has inherited two genes coding surface virus antigens (hemagglutinin and neuraminidase) from the epidemic virus and the rest six genes coding non-glycated proteins, from the attenuation donor A/PR/8/59/M2 (H1N1).

EFFECT: presented inventions can be used in preparing a live influenza intranasal vaccine for adults and children.

3 cl, 2 dwg, 4 tbl, 1 ex

Similar patents RU2556833C2

Title	Year	Author	Number
USING INFLUENZA VIRUS STRAIN A/17/NEW CALEDONIA/99/145 (H1N1) AS ATTENUATION DONOR FOR PRODUCING VACCINATING STRAINS OF LIVING INFLUENZA VACCINE SUBTYPE H2N2, VACCINATING INFLUENZA VIRUS STRAINS A/17/CALIFORNIA/66/4412 (H2N2) AND A/17/TOKYO/67/912 (H2N2) (VERSIONS)	2011	Isakova-Sivak Irina Nikolaevna Rudenko Larisa Georgievna	RU2556834C2
VACCINE STRAIN OF A/17/BRISBANE/07/28 (H1N1) INFLUENZA VIRUS FOR PREPARING LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN	2010	Kiseleva Irina Vasil'Evna Larionova Natal'Ja Valentinovna Rudenko Larisa Georgievna Aleksandrova Galina Ibragimovna	RU2416641C1
INFLUENZA VIRUS STRAIN FOR PRODUCING LIVE AND INACTIVATED INFLUENZA VACCINE	2011	Desheva Julija Andreevna Rudenko Larisa Georgievna Aleksandrova Galina Ibragimovna Smolonogina Tat'Jana Anatol'Evna	RU2464309C1
STRAIN OF INFLUENZA VIRUS GKV 2389 FOR PRODUCTION OF LIVING INTRANASAL AND INACTIVATED INFLUENZA VACCINE	2006	Desheva Julija Andreevna Rudenko Larisa Georgievna Aleksandrova Galina Ibragimovna	RU2318871C1
VACCINE STRAIN OF A/17/SOLOMON ISLANDS/06/9 (H1N1) INFLUENZA VIRUS FOR PREPARING LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN	2010	Larionova Natal'Ja Valentinovna Kiseleva Irina Vasil'Evna Rudenko Larisa Georgievna Aleksandrova Galina Ibragimovna	RU2422518C1
INFLUENZA VIRUS STRAIN FOR PRODUCING LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN	2011	Desheva Julija Andreevna Rudenko Larisa Georgievna Aleksandrova Galina Ibragimovna	RU2464311C1
ATTENUATED COLD-ADAPTED STRAIN OF INFLUENZA VIRUS A/KRASNODAR/101/59/35(H2N2) FOR OBTAINING STRAINS OF LIVE INTRANASAL INFLUENZA VACCINE	2007	Gendon Jurij Zakharovich Markushin Stanislav Georgievich Akopova Irina Ivanovna Koptjaeva Irina Borisovna Tsfasman Tat'Jana Mikhajlovna	RU2354695C1
VACCINE STRAIN OF FLU VIRUS A/17/CALIFORNIA/2009/38 (H1N1) FOR PROFUCTION OF LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN	2009	Larionova Natal'Ja Valentinovna Kiseleva Irina Vasil'Evna Rudenko Larisa Georgievna Aleksandrova Galina Ibragimovna	RU2413765C1
REASSORTANT A/17/NEW CALEDONIA/99/79(H1N1) INFLUENZA VIRUS STRAIN FOR PRODUCING LIVE INFLUENZA INTRANASAL VACCINE	2011	Desheva Julija Andreevna Rudenko Larisa Georgievna Aleksandrova Galina Ibragimovna	RU2464310C1
INFLUENZA VIRUS STRAIN A/47/PEKING/95/35 (H1N1) FOR PRODUCTION OF LIVE INFLUENZAL INTRANASAL VACCINE FOR BABIES	1999	Kiseleva I.V. Aleksandrova G.I. Rudenko L.G. Naumenko Z.S. Klimov A.I.	RU2159810C1

RU 2 556 833 C2

Authors

Isakova-Sivak Irina Nikolaevna

Rudenko Larisa Georgievna

Dates

2015-07-20—Published

2011-07-12—Filed