NUCLEIC ACID COMPLEX AND COMPOSITION FOR NUCLEIC ACID DELIVERY Russian patent published in 2012 - IPC A61K48/00 A61K31/724 A61K9/127 

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to medicine and represents a complex of nucleic acid and strongly branched cyclic dextrin representing glucan of a degree of polymerisation 50-5000, containing an internal branched cyclic structural fragment formed by alpha-1,4-glucoside bonds and at least one alpha-1,6-glucoside bonds and an external branched structural fragment bound to the internal branched cyclic structural fragment. The group of inventions also involves a composition containing of the diacylphosphatidylcholine, at least one compound specified in cholesterol, and a primary aliphatic amine, as well as the use and the method for cell delivery.

EFFECT: group of inventions provides low toxicity and high degree of safety; it is able to maintain the stable content of nucleic acid in a cell.

14 cl, 6 ex, 3 dwg