FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to chemical-pharmaceutical industry and represents method of preparing injected calcium-phocphatic bone cement in form of apatite, releasing gembisphosphonic compound, and claimed method includes addition of bisphosphonic acid or its salt or solid calcium precursor, modified by bisphosphonic acid or its salt, in solid phase of cement or in liquid phase of cement, and claimed solid calcium precursor is selected from calcium orthophosphates and non-phosphate calcium salts, such as CaCO3 or CaSO4.
EFFECT: invention ensures obtaining calcium-phosphatic bone cement, characterised by time of hardening, suitable for surgical application; which has strength for compression, close to strength for bone compression; which is resolvable for its replacement by new bone material; which ensures release of inhibitor of bone tissue resorption.
21 cl, 10 ex, 5 dwg
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Authors
Dates
2012-11-10—Published
2008-02-13—Filed