METHOD OF TREATING LOCALLY ADVANCED UNRESECTABLE OESOPHAGEAL CANCER Russian patent published in 2012 - IPC A61N5/00 A61N5/10 A61B18/18 A61K31/282 A61K31/337 A61K31/513 A61K31/7068 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, oncology, and may be used for treating locally advanced unresectable oesophageal cancer. Preliminary argon-plasma coagulation of a tumour is followed by high-power intraluminal brachytherapy on 1^st, 8^th and 15^th day of the therapeutic course at single basic dose 7 Gy combined with the intravenous introduction of taxane preparations and carboplatine. Further, the tumour is exposed to tele-radiation at single basic dose 1.8 Gy, 5 fractions/week, SOD 40-45 Gy, supported by the use of fluoropyrimidine derivatives in the following doses: oral administration of capecitabine 600 mg/m² in degree 0-1 dysphagia in days of radiation therapy, intravenous infusions of 5-fluorouracil 1000 mg/m² in degree 2-3 dysphagia every week.

EFFECT: method provides optimising cytoreductive reaction of chemoradiation therapy components and more complete response of the tumour with relieved severe systemic and local reactions.

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