METHOD OF OPTIMISING TREATMENT OF LOCALLY ADVANCED AND INOPERABLE CANCER OF ESOPHAGUS Russian patent published in 2010 - IPC A61N5/06 A61B18/04 A61B18/12 A61M36/00 A61K51/00 A61K31/337 A61K31/282 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, oncology, and can be used for treatment of locally advanced and inoperable cancer of esophagus. For this purpose before beginning chemoradiation therapy argon plasma coagulation of tumour is performed. After that on 1-st, 8-th and 15-th day of the course intraluminal brachytherapy with high power dose 5-10 Curie with single dose 7 Gy is carried out. In addition, on 1-st, 8-th and 15-th day of the course intravenously taxoter 45 mg/m² and carboplatin AUC 2 are introduced. After that teleirradiation SFD 1.8 Gy 5 fractions/week TFD 40-45 Gy is carried out.

EFFECT: method allows to increase efficiency of chemotherapeutic and radiation effect after preliminarily eliminated by argon plasma coagulation tumour stenosis of esophagus, succession of treatment stages allows to ensure maximal response of tumour, enhance degree of tumour regress and reduce probability of metastasis.

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