FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to compounds of formula I: 
where R, R1, R2, R3, R4, x and z are determined in items of the invention formula, useful as inhibitors of voltage-gated sodium channels.
EFFECT: invention claims pharmaceutically acceptable compositions, which contain said compounds and methods of applying such compositions for treatment of various diseases.
76 cl, 3 tbl
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