FIELD: chemistry.
SUBSTANCE: invention relates to novel 5-O-derivatives of avermectin of general formula I: 
where: A=Me or Et, R=OH, OAlk or NR1R2, where: R1, R2=H, Alk, X=-(CH2)n-, where: n-2-12, 
where: R3, R4, R5, R6=H, Alk, Ph or Ha1; n=1-5; or X is a heterocyclic fragment. The invention also relates to a method of producing said compounds.
EFFECT: obtaining novel compounds which exhibit antiparasitic activity and can be used as antiparasitic agents in medicine, veterinary agriculture, fish industry and other sectors associated with animal breeding as antiparasitic agents.
6 cl, 1 tbl, 27 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 5-O-SUCCINOYL AVERMECTIN, SYNTHESIS METHOD THEREOF AND ANTIPARASITIC AGENT BASED THEREON | 2011 |
|
RU2453553C1 |
| ANTIPARASITIC AGENT | 2014 |
|
RU2554074C1 |
| INSECTICIDAL AGENT | 2014 |
|
RU2554350C1 |
| 4"-O,5-O-DI(METHYLCARBAMATE)IVERMECTIN, METHOD OF ITS PRODUCTION AND ANTIPARASITIC AGENT BASED THEREON | 2016 |
|
RU2627277C1 |
| AVERMECTIN B 5-O-SUCCINATE, METHOD FOR PRODUCTION THEREOF AND ANTI-PARASITIC AGENT BASED THEREON | 2017 |
|
RU2670092C1 |
| AVERMECTIN B 5-O-HEMISUCCINATE AMIDES, METHOD FOR PRODUCTION THEREOF AND ANTI-PARASITIC AGENTS BASED THEREON | 2017 |
|
RU2670107C1 |
| IVERMECTIN 5,4"-BIS[(ARYL)AMINO](THIOXO)ACETATES, METHOD FOR PRODUCTION THEREOF AND ANTIPARASITIC AGENTS BASED THEREON | 2017 |
|
RU2670202C1 |
| MEANS FOR ANIMAL ARACHNOSES TREATMENT | 2016 |
|
RU2635191C1 |
| METHOD FOR DETERMINATION OF NEMATOCIDAL ACTIVITY OF AVERMECTIN CONTAINING SUBSTANCES AND PREPARATIONS | 2016 |
|
RU2637087C1 |
| PREPARATION FOR COMBATING WITH INSECTS-CERATOPHAGES | 2016 |
|
RU2630316C1 |
