FIELD: biotechnology.
SUBSTANCE: invention relates to the field of antiparasitic agents, namely the previously unknown antiparasitic agent which is a compound - 5-O-succinoylivermectin of formula 1 
, which can be used in medicine, veterinary medicine as well as in agricultural, fishing industry and in other fields associated with breeding of animals, as a component for antiparasitic agents. This compound is obtained by interaction of ivermectin B with succinic anhydride in the medium of an organic solvent such as in pyridine, or in a mixture of dimethylformamide and pyridine, in the presence of a catalyst of amine type, such as for example triethylamine, dimethylaminopyridine.
EFFECT: creation of a new highly effective antiparasitic agent, which is 5-O- succinoylivermectin of formula I, resistant to the action of sunlight, which then can be used as a highly effective antiparasitic agent for pest control in lower concentrations.
1 tbl, 23 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 5-O-SUCCINOYL AVERMECTIN, SYNTHESIS METHOD THEREOF AND ANTIPARASITIC AGENT BASED THEREON | 2011 |
|
RU2453553C1 |
| 5-O-DERIVATIVES OF AVERMECTIN, METHOD FOR PRODUCTION THEREOF AND ANTIPARASITIC AGENTS BASED THEREON | 2011 |
|
RU2472801C1 |
| 4"-O,5-O-DI(METHYLCARBAMATE)IVERMECTIN, METHOD OF ITS PRODUCTION AND ANTIPARASITIC AGENT BASED THEREON | 2016 |
|
RU2627277C1 |
| AVERMECTIN B 5-O-SUCCINATE, METHOD FOR PRODUCTION THEREOF AND ANTI-PARASITIC AGENT BASED THEREON | 2017 |
|
RU2670092C1 |
| IVERMECTIN 5,4"-BIS[(ARYL)AMINO](THIOXO)ACETATES, METHOD FOR PRODUCTION THEREOF AND ANTIPARASITIC AGENTS BASED THEREON | 2017 |
|
RU2670202C1 |
| AVERMECTIN B 5-O-HEMISUCCINATE AMIDES, METHOD FOR PRODUCTION THEREOF AND ANTI-PARASITIC AGENTS BASED THEREON | 2017 |
|
RU2670107C1 |
| INSECTICIDAL AGENT | 2014 |
|
RU2554350C1 |
| METHOD FOR DETERMINATION OF NEMATOCIDAL ACTIVITY OF AVERMECTIN CONTAINING SUBSTANCES AND PREPARATIONS | 2016 |
|
RU2637087C1 |
| MEANS FOR ANIMAL ARACHNOSES TREATMENT | 2016 |
|
RU2635191C1 |
| PREPARATION FOR COMBATING WITH INSECTS-CERATOPHAGES | 2016 |
|
RU2630316C1 |
