FIELD: medicine.
SUBSTANCE: invention relates to the field of medical diagnostics, in particular to a method for predicting the risk of developing a combination of uterine fibroid and endometrial hyperplastic processes. Method includes isolation of DNA from peripheral venous blood, analysis of a combination of rs4633, rs757647, rs555621 gene polymorphisms. Risk factor for the development of uterine fibroids and endometrial hyperplastic processes in women is the combination of the rs4633 C allele with the rs757647 C allele and the rs555621 A allele.
EFFECT: invention provides criteria for assessing the risk of developing a combination of uterine fibroids and endometrial hyperplastic processes in women of Russian nationality, natives of the Central Black Soil Region, based on data on a combination of genetic variants of rs4633, rs757647 and rs555621 loci.
1 cl, 3 ex
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Authors
Dates
2019-02-05—Published
2018-03-16—Filed