FIELD: medicine.
SUBSTANCE: invention aims at the prediction of a risk of degree 2-3 placental insufficiency with foetal growth delay syndrome in the pregnant women. Peripheral venous blood is sampled to recover DNA. 20210G/A FII, 1691G/A FV and 10976G/A FVII coagulation factor genes are analysed. Observing 10976G FVII allele and 10976GG FVII genotype enables predicting a high risk of degree 2-3 placental insufficiency with foetal growth delay syndrome in the pregnant women. The presence of combinations of 20210GG FII genotype and 10976A FVII alleles; 20210G FII, 10976A FVII alleles with 1691GG FV genotype or 20210G FII and 10976A FVII alleles provides predicting a low risk of degree 2-3 placental insufficiency with foetal growth delay syndrome in the pregnant women.
EFFECT: effective method for the prediction of degree 2-3 placental insufficiency with foetal growth delay syndrome in the pregnant women.
3 dwg, 1 tbl, 1 ex
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Authors
Dates
2015-02-10—Published
2013-10-31—Filed