METHOD FOR PREDICTION OF RISK OF PREECLAMPSIA BY COMBINATION OF CYTOKINE GENES Russian patent published in 2015 - IPC G01N33/52 C12Q1/68 

Abstract RU 2568891 C1

FIELD: medicine.

SUBSTANCE: prediction of a risk of preeclampsia in Russian females, natives of the Central Black Earth Region is ensured by recovering DNA from peripheral venous blood to analyse cytokine gene polymorphism. The minor risk of preeclampsia is predicted if observing a combination of three genetic variations of four gene polymorphisms: G I-TAC (rs4512021) and +36 GG TNFR1; +250 A Ltα, G I-TAC (rs4512021) and +36 GG TNFR1; +250 G Ltα (rs909253), +36 A TNFR1 (rs767455), -403 G/A RANTES (rs2107538).

EFFECT: using the invention is expected to provide the more effective identification of the risk of preeclampsia.

4 dwg, 2 tbl, 4 ex

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RU 2 568 891 C1

Authors

Churnosov Mikhail Ivanovich

Kaganovich Evgeniya Nikolaevna

Dobrodomova Irina Sergeevna

Batlutskaya Irina Vitalevna

Polonikov Aleksej Valerevich

Dates

2015-11-20Published

2014-08-28Filed