FIELD: chemistry.
SUBSTANCE: invention relates to biosensors and can be used in studying proteins via a luminescence technique. A protein luminescence-activating hybrid complex is obtained through ultrasonic treatment of a protein which contains aromatic amino acids in a physiological solution in the presence of phosphorus Y0.95Hr0.05VO4 or Y0.95Er0.05YO3Cl. The complex contains donor-acceptor pairs.
EFFECT: use of the invention increases luminescence of the investigated protein and reduces labour input of the protein labelling procedure, widens the range of proteins analysed using a luminescence technique, and lowers the technological level of the process of obtaining donor-acceptor pairs in the protein luminescence-activating hybrid complex.
2 ex
Title | Year | Author | Number |
---|---|---|---|
CONDUCTIVE COMPOSITE MATERIAL BASED ON CONJUGATED POLYMERS WITH GRAPHENE | 2022 |
|
RU2804778C1 |
DEVICE MEASURING CONCENTRATION OF OXYGEN IN LIQUIDS AND GASES | 1999 |
|
RU2156969C1 |
METHOD OF DETECTION OF IONS OF METALS IN SOLUTIONS | 1992 |
|
RU2049986C1 |
METHOD FOR FORMING FLUORESCENT THIN FILMS BASED ON MIXED SUBSTITUTED PHTALOCYANINE DERIVATIVE | 2020 |
|
RU2806720C2 |
METHOD OF FORMATION OF LIGHT-ACCUMULATING SYSTEMS | 2000 |
|
RU2194735C2 |
NOVEL PROTEIN CONJUGATE AND USE THEREOF FOR PREVENTING OR TREATING NON-ALCOHOLIC STEATOHEPATITIS, OBESITY AND DIABETES | 2021 |
|
RU2822001C1 |
HIGH-EFFICIENCY SCREENING COMPOUNDS MODULATING EXPRESSION OF CELL MACROMOLECULES | 2012 |
|
RU2612017C2 |
LUMINESCENT SENSOR FOR MULTIPLEX (SPECTRAL-TIME) DETECTION OF ANALYTES IN AQUEOUS MEDIA AND METHOD FOR PRODUCTION THEREOF | 2020 |
|
RU2769756C1 |
METHOD OF BIOOBJECT MARKING IN AQUEOUS SOLUTION | 2010 |
|
RU2425887C1 |
METHODS AND APPLICATIONS INCLUDING HEME PROTEIN 1 | 2009 |
|
RU2520748C2 |
Authors
Dates
2013-02-20—Published
2011-11-23—Filed