METHOD FOR FREEZE DRYING PHARMACEUTICAL PREPARATIONS Russian patent published in 2013 - IPC F26B5/06 

Abstract RU 2476790 C2

FIELD: chemistry.

SUBSTANCE: method of obtaining a lyophilisate of a pharmaceutical preparation involves immersing a cellular carrier into the solution of the pharmaceutical preparation to form films of the solution in cells of the carrier, putting the carrier into a freezing zone and then into a heating zone where the solution is dried, with subsequent removal of the lyophilisate of the pharmaceutical preparation, wherein moisture content is controlled in each cell in the heating zone by positioning a fibre-optic sample of a transmission-type spectrophotometer operating in the near-infrared range or which detects Raman shift.

EFFECT: simple process of production, high output of the end product, enabling automation of the process, low cost of the product, enabling inspection of moisture of the end product, high quality of the end product.

8 cl

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RU 2 476 790 C2

Authors

Puchkov Nikolaj Anatol'Evich

Dates

2013-02-27Published

2011-05-31Filed