METHOD FOR PREDICTION OF DEVELOPING ACUTE PANCREATITIS FOLLOWING ENDOSCOPIC TRANSPAPILLARY INTERVENTIONS Russian patent published in 2013 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: for the purpose of prediction of developing acute pancreatitis following an endoscopic transpapillary intervention in the patients suffering bile hypertension syndrome, demographics and laboratory findings are analysed along with the preoperative examination; that is followed by calculating 'a pancreatogenic index' (PGI) by formula as total risk factors (F_r) of developing acute pancreatitis: PGI=F_r1+F_r2+F_r3+F_r4 taking into account the following data: F_r1 - age, years: before 40 F (females)+1, M (males)+3; 41-60 F+2, M-1; 60 and older F-1, M+1; F_r2 - underlying disease: gallstone disease F+2, M-1; postcholecystectomy syndrome F-1, M-2; pancreatobiliary tumours F+2, M-1; virsungolithiasis F+3, M-1; F_r3- bilirubin, mcmole/l (normal below 20.6): normal F+1, M-2; below 100 F-1, M+1; 101-200 F+2, M+3; 200 and more F+3, M-2; F_r4 - amylase, units/l (normal below 220): below 100 F-1, M-2; 101-200 F+1, M+1; 200 and more F+3, M+3, and if PGI≥0, a high risk of developing acute postoperative pancreatitis is predicted, while PGI<0 enables estimating a risk to be minimal.

EFFECT: method provides more accurate prediction of developing acute pancreatitis following endoscopic transpapillary interventions due to estimating a degree of risk of its onset in a specific patient.

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