METHOD OF DETERMINING INDIVIDUAL RISK OF ACUTE PANCREATITIS DEVELOPMENT AFTER ENDOSCOPIC TRANSPAPILLARY INTERVENTION Russian patent published in 2014 - IPC A61B5/00 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, in particular to endosurgery. To determine individual risk of acute pancreatitis development after endoscopic transpapillary intervention, analysis of demographic data and biochemical blood test is carried out. In the course of pre-operation examination index of risk of acute pancreatitis development (IRPD) is determined by formula: IRPD=(A₁×2/A_n+B_t/100)×(40/C₁)×D×E, where: A₁ stands for values of patient's blood amylase; A_n stands for normal maximal values of blood amylase; ; B₁ stands for value of patient's blood bilirubin; C₁ stands for patient's age; D stands for patient's sex: D=2, if patient is female and D=1, if patient is male; E stands for character of the main disease: E=1 in patients with tumours of hepatopancreatobiliary zone; E=2 for patients with choledocholithiasis, E=3 in patients with virsungolithiasis, with stenosis of major duodenal papilla, as well as in patients with combination of choledocholithiasis and stenosis of major duodenal papilla. If IRPD <0.5, risk of acute pancreatitis development is lower than 2%; if IRPD =0.5-0.99 risk of development constitutes 2-10%; if IRPD=1-1.99, risk of development is 11-20%; if IRPD=2-3.99 - 21-30%; if IRPD=4-5 - 31-40%; if IRPD>5 - more than 40%.

EFFECT: method makes it possible to increase accuracy of determining individual risk of acute pancreatitis development after endoscopic transpapillary intervention due to determination of IRPD, based on multi-factor analysis of informative criteria of particular patient.

2 ex