FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to chemical-pharmaceutical industry and concerns a method for preparing a method for preparing betulin 3-acetate-28-sulphate of formula I 
- that is a biologically active substance being of the utmost interest for medicine. Betulin 3-acetate-28-sulphate is sulphated in N,N-dimethylformamide by a complex of SO3-dimethylformamide at temperature 30-50°C for 1-2 hours to recover an end product.
EFFECT: synthesis of new water-soluble sulphated betulin derivatives, extended range of the sulphatising agent, simplified process ensured by using liquid SO3.
1 cl, 1 ex
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