FIELD: chemistry.
SUBSTANCE: invention relates to method of obtaining derivatives of betulin 3-acetate-28-sulphate of formula I, which consists in sulphation of betulin 3-acetate in N,N-dimethylformamide with mixture of sulphamic acid and urea at temperature 30-40°C for 2.0-2.5 hours, separation of product by cooling reaction mass, its dilution with water, extraction with butyl or isoamyl alcohol, water washing, processing of alcohol extract with the following concentration of alcohol layer and separation of target product.
EFFECT: method improvement.
4 cl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
RU2571101C1 |
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