BIOPOLYMERIC MATRIX FOR PROLIFERATION OF CELLS AND REGENERATION OF NERVOUS TISSUES Russian patent published in 2013 - IPC A61K38/39 A61K35/12 B82B1/00 A61K47/02 A61P25/00 

FIELD: medicine.

SUBSTANCE: invention relates to experimental medicine, in particular to biopolymeric matrix for proliferation of cells and regeneration of nervous tissues. Biopolymeric matrix is developed on the basis of heterogeneous collagen-containing structure, which consists of microparticles of collagen with size 30-300 mcm, dispersed in homogeneous gel of collagen, and containing neutral stem cells and stimulating additive in form of silicon nanoparticles with size 50-150 nm in quantity 1·10^-3-1·10^-2 wt %. Additive in form of silicon nanoparticles in applied for stimulation of cells proliferation and regeneration of nervous tissues. Nanoparticles of silicon are obtained by method of laser-induced pyrolysis of monosilane SiH₄. Assessment in vitro of biological action of biopolymeric matrix (influence on viability and proliferation of cells) in carried out with application of neutral stem cells.

EFFECT: biopolymeric matrix stimulates proliferation of cells and regeneration of nervous tissues and has biocompatible properties.

3 cl, 1 dwg, 1 tbl