FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to organic chemistry, particularly to a method for preparing 3-(m-, n-methylphenyl)-1,5,3 -dithiazepanes of general formula (1):
which consists in the fact that a mixture of formaldehyde and 1,2-ethandithiole prepared at 20°C for 30 min is added with the catalyst Sm(NO3)3·6H2O, m-, or n-methylaniline at molar ratio of m-, or n-methylaniline : formaldehyde : 1,2-ethandithiole : Sm(NO3)3·6H2O = 10 : 20 : 10 : 0.5, to be mixed at room (~20°C) temperature for 20-40 min in chloroform.
EFFECT: what is developed is a method for preparing new 3-(m-,n-methylphenyl)-1,5,3-dithiazepanes which can find application as antibacterial, antimycotic and antiviral agents as biologically active complexing agents, selective sorbents and extractants of precious metals, special agents for bacterial activity suppression in various technical media.
1 cl, 1 tbl, 1 ex
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