FIELD: chemistry.
SUBSTANCE: invention relates to a method of obtaining 3-aryl-1,5,3-dithiazepanes of general formula where R = H (a), m-CH3 (b), p-CH3 (c), o-OCH3 (d), m-OCH3 (e), p-OCH3 (f), o-NO2 (g), m-NO2 (h), p-NO2 (i), characterised by the fact that N1,N1,N6,N6-tetramethyl-2,5-dithiahexane-1,6-diamine is subjected to interaction with arylamine (aryl = phenyl, m- and p-methylphenyl, o-, m- and p-methoxyphenyl, o-, m- and p-nitrophenyl) in the presence of a catalyst FeCl3·6H2O in a molar ratio N1,N1,N6,N6-tetramethyl-2,5-dithiahexane-1,6-diamine: arylamine:FeCl3·6H2O=10:10:(0.3-0.7) at a temperature of ~60°C and atmospheric pressure in chloroform as a solvent for 50-80 minutes.
EFFECT: elaborated is the method of obtaining derivatives of 3-aryl-1,5,3-dithiazepanes, which can be applied as antibacterial, antifungal and antiviral agents, as biologically active complexants, selective sorbents and extractants of precious metals, special reagents for the suppression of bacteria activity in various technical media.
Title | Year | Author | Number |
---|---|---|---|
METHOD OF OBTAINING 3-ARYL-1,5,3-DITHIAZEPANES | 2013 |
|
RU2536132C2 |
METHOD FOR OBTAINING N-CYCLOALKYL SUBSTITUTED 1,5,3-DITHIAZEPANES | 2017 |
|
RU2664654C2 |
METHOD OF PRODUCING 3-ARYL-1,5,3-DIOXAZEPANES | 2012 |
|
RU2529507C2 |
METHOD FOR OBTAINING 3- AND 4-(1,5,3-DITHIAZACYCLOALKAN-3-YL)BENZAMIDES | 2014 |
|
RU2574073C2 |
METHOD OF OBTAINING 3-HETARYL-1,5,3-DITHIAZEPINANES | 2012 |
|
RU2529502C2 |
METHOD OF PRODUCING N-(1,5,3-DITHIAZEPAN-3-YL)AMIDES | 2011 |
|
RU2482114C2 |
METHOD OF OBTAINING 3-ARYL-1,5,3-DITHIAZOCANES | 2012 |
|
RU2538600C2 |
METHOD OF OBTAINING N-ARYL--1,5,3-DITHIAZEPANES | 2011 |
|
RU2466996C1 |
METHOD OF OBTAINING 3-ARYL-1,5,3-DITHIAZEPANES | 2011 |
|
RU2466997C1 |
METHOD OF PRODUCING N,N-BIS-[(1,5,3-DITHIAZEPAN-3-YL)ALKYL]AMINES | 2014 |
|
RU2591196C2 |
Authors
Dates
2014-12-20—Published
2013-01-28—Filed