METHOD OF PREDICTING COURSE OF MODERATE TO SEVERE CHRONIC OBSTRUCTIVE LUNG DISEASE Russian patent published in 2013 - IPC A61B5/08 A61B5/87 A61B5/91 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to pulmonology and can be used for predicting course of moderate to severe chronic obstructive lung disease (COLD). Volume of forced exhalation for the first second (VFE₁) is measured. Bronchi-provoking pharmacological test with 0.33% methacholine solution is performed. Change of volume of forced exhalation for the first second (ΔVFE₁) from the initial value is registered. On the basis of said parameters determined are: post-bronchodilation residual volume of lungs and degree of hypersensitivity of respiratory ways, which are considered to be a risk factor. Other risk factors: patient's age, disease duration, number of exacerbations pre year, are also taken into account. Each risk factor is given a numerical value and gradation, which are used to determine prognostic coefficients F₁ and F₂ with further comparison of these values. If F₂ is larger than F₁, unfavourable course of COLD with progressing dyspnea is predicted. If F₁ value is larger than F₂, favourable clinical course of disease with low risk of severe dyspnea development is predicted.

EFFECT: method makes it possible to predict clinical course of said disease and activate pathogenetically justified therapy in due time.

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