FIELD: medicine.
SUBSTANCE: invention describes a method of gradually optimising a dose of 5-FU administered by continuous infusion to the patients being treated with the FOLFOX or similar regime, on the basis of the plasma concentration of 5-FU measured during the preceding continuous infusion of 5-FU, and described in the given application of the decision procedure. The present invention also refers to a method of treating a patient with cancer wherein the dose of 5-FU administered into continuous infusion in each FOLFOX cycle or similar therapeutic cycle, optimised with using the decision procedure in accordance with the invention.
EFFECT: gradually optimising the doses of 5-FU.
14 cl, 3 dwg, 8 tbl, 1 ex
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Authors
Dates
2013-05-20—Published
2008-09-26—Filed