FIELD: chemistry.
SUBSTANCE: invention refers to compounds of formula I: wherein a dash line represents an optional double bond; R1 means phenyl, naphthyl, pyridyl optionally substituted by one or two substitutes optionally substituted from halogen, C1-C6 alkyl, mono-halo C1-C6 alkyl, di-halo C1-C6 alkyl, CF3; R2 means H, methyl, halogen; R3 and R4 optionally mean, CF3, halo, C1-C3 alkyl wherein C1-C3 alkyl groups are optionally substituted by one or more halogen atoms; X=O; q=0; R5 means C1-C6 alkyl or its pharmaceutically acceptable salt.
EFFECT: compounds possess potassium channel modulating activity that enables using them in pharmaceutical compositions.
28 cl, 1 tbl, 2 dwg
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Authors
Dates
2013-05-27—Published
2008-08-12—Filed