FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing 2,3-disubstituted indoles of general formula (I): 
, where the method involves the following steps: a) reaction of bromine diol (i): 
with dialkoxyborane in the presence of a ligand, a palladium catalyst, preferably selected from Pd(OAc)2, PdCl2, PdBr2, Pd2(dba)3, Pd2(dba)3.CHCl3, [Pd(ally)Cl]2,- Pd(CH3CN)2Cl2, Pd(PhCN)2Cl2, Pd/C and encapsulated Pd and a base to obtain a compound of general formula 
or, alternatively, reaction of compound (i) with a magnesium compound containing 3 alkyl groups, with subsequent treatment with a borate to obtain a compound of general formula ii given above; b) reaction of the product from step (a) with R2-Hal to obtain a compound of general formula I; where: R denotes (C1-C6)alkyl; R2 denotes: 
, 
, 
, 
, 
,
, 
, 
, 
, 
;
R3 denotes cyclopentyl: X denotes carboxymethyl; Hal denotes Br or I; or pharmaceutically acceptable salt thereof.
EFFECT: higher efficiency.
12 cl, 4 dwg, 2 tbl, 14 ex
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