AGENT FOR ANTIPLATELET, ANTI-INFLAMMATORY AND CYTOPROTECTIVE THERAPY Russian patent published in 2013 - IPC A61K38/00 A61K38/46 A61P29/00 

Abstract RU 2483746 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine, and concerns an agent for prevention and treatment of cardiovascular diseases. The peptide 3-mercaptopropionyl-Phe-Ile-lle-Arg-Lys-Pro-Asp-Lys-NH2 is synthetised which has greater availability and lower price than known analogues; it possesses the antiplatelet, anti-inflammatory and cytoprotective properties.

EFFECT: invention provides reduced spontaneous thrombocyte aggregation, inflammation inhibition by reducing histamine secretion, cell protection against neurotoxic actions of thrombin.

1 cl, 4 ex

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RU 2 483 746 C1

Authors

Rumsh Lev Davydovich

Strukova Svetlana Mikhajlovna

Gorbacheva Ljubov' Rufehl'Evna

Bespalova Zhanna Dmitrievna

Sidorova Marija Vladimirovna

Frid Dmitrij Aleksandrovich

Fel'Dman Boris Mordkovich

Burjachkovskaja Ljudmila Ivanovna

Dates

2013-06-10Published

2012-05-17Filed