NEW PYRROL DERIVATIVE HAVING UREIDE AND AMINOCARBONYL GROUPS AS SUBSTITUTES Russian patent published in 2013 - IPC C07D207/416 C07D401/04 C07D401/12 C07D403/12 C07D413/12 C07D417/12 A61K31/40 A61K31/4025 A61P27/02 

Abstract RU 2485101 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pyrrol derivatives of formula (1): or a pharmaceutically acceptable salt thereof wherein the values A, R1-R3, n are specified in clause 1 of the patent claim.

EFFECT: compounds (1) inhibit activity against the interleukin IL-6 production that allows using them both in pharmaceutical compositions, and in a prophylactic drug for ocular inflammatory disease.

23 cl, 2 tbl, 22 ex

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RU 2 485 101 C2

Authors

Kavasima Kendzi

Enomoto Khirosi

Isizaka Noriko

Jamamoto Minoru

Kudou Kazukhiro

Mjurai Masaaki

Inaba Takaaki

Okamoto Kazuesi

Dates

2013-06-20Published

2008-02-26Filed