Show metadata Hide metadata

(19)

(11)

2 470 918

(13)

(51)

IPC

C07D209/42(2006-01-01)

C07D401/04(2006-01-01)

C07D403/04(2006-01-01)

C07D405/04(2006-01-01)

C07D409/04(2006-01-01)

C07D413/04(2006-01-01)

C07D417/04(2006-01-01)

A61K31/404(2006-01-01)

A61K31/4439(2006-01-01)

A61P27/02(2006-01-01)

A61P27/06(2006-01-01)

(21) (22)

Application

2009131031/04, 2008-01-15

(24)

Start date

2008-01-15

(22)

Actual filing date

2008-01-15

(45)

Published

2012-12-27

(72)

Inventor

Enomoto KhirosiKavasima KendziKudou KazukhiroJamamoto MinoruMjurai MasaakiInaba TakaakiIsizaka Noriko

(73)

Holder

Santen Farmas'Jutikal Ko., Ltd.

NOVEL INDOLE DERIVATIVES HAVING IκB KINASE β INHIBITING ACTIVITY Russian patent published in 2012 - IPC C07D209/42 C07D401/04 C07D403/04 C07D405/04 C07D409/04 C07D413/04 C07D417/04 A61K31/404 A61K31/4439 A61P27/02 A61P27/06

Abstract RU 2470918 C2

FIELD: chemistry.

SUBSTANCE: invention relates to indole derivatives or pharmaceutically acceptable salts thereof of general formula (1): , where values of R¹, R², m are given in claim 1.

EFFECT: compounds have inhibiting activity on IKKβ, which enables their use as a preventive or therapeutic agent for treating IKKβ mediated diseases.

26 cl, 1 tbl, 29 ex

Similar patents RU2470918C2

Title	Year	Author	Number
NOVEL INDOLE DERIVATIVE CONTAINING CARBAMOYL GROUP, UREIDE GROUP AND SUBSTITUTED OXY GROUP	2009	Kavasima Kendzi Enomoto Khirosi Jamamoto Minoru Mjurai Masaaki	RU2503661C2
NEW PYRROL DERIVATIVE HAVING UREIDE AND AMINOCARBONYL GROUPS AS SUBSTITUTES	2008	Kavasima Kendzi Enomoto Khirosi Isizaka Noriko Jamamoto Minoru Kudou Kazukhiro Mjurai Masaaki Inaba Takaaki Okamoto Kazuesi	RU2485101C2
COMBINED TREATMENT OF MALIGNANT NEOPLASM USING SULPHONAMIDE COMPOUND AND IMMUNOREGULATOR	2020	Ueno, Hiroyuki Tsukioka Sayaka	RU2820817C2
NOVEL PYRROLE DERIVATIVE HAVING AS SUBSTITUTES UREIDE GROUP, AMINOCARBONYL GROUP AND BICYCLIC GROUP, OPTIONALLY SUBSTITUTED	2009	Kavasima Kendzi Kavasima Noriko Enomoto Khirosi Jamamoto Minoru Mjurai Masaaki	RU2500669C2
COMBINATION CANCER THERAPY USING AZABICYCLO COMPOUND	2014	Muraoka Khiromi Kanokh Akira	RU2657783C2
INHIBITOR OF ACTIVITY OF CHOLESTEROL ESTERIFIED TRANSPORT PROTEIN, PROPHYLACTIC OR THERAPEUTIC AGENT, DERIVATIVES OF BIS-(2-AMIDOPHENYL)-DISULFIDE OR AMIDOTHIOPHENOL	1998	Sinkai Khisasi Maeda Kimija Okamoto Khirosi	RU2188631C2
CANCER CHEMOTHERAPY USING AZABICYCLO COMPOUND	2018	Ohkubo, Shuichi	RU2821034C2
HETEROCYCLIC COMPOUNDS AS RET KINASE INHIBITORS	2017	Jordan Allan Newton Rebecca Waszkowycz Bohdan Sutton Jonathan Mark Hynd George Paoletta Silvia Fordyce Euan Alexander Fraser	RU2742115C2
DERIVATIVES OF AROMATIC AMINES ELICITING EFFECT INHIBITING OAC, METHOD OF THEIR SYNTHESIS AND INHIBITOR OF нOAC	1997	Esaki Toru Makino Tosikhiko Nisimura Josikazu Nagafudzi Tosiaki	RU2193554C2
COMBINED THERAPY INCLUDING SGLT INHIBITORS AND DPP4 INHIBITORS	2009	Ueta Kiitiro Arakava Kendzi Matsusita Jasuaki	RU2481106C2

RU 2 470 918 C2

Authors

Enomoto Khirosi

Kavasima Kendzi

Kudou Kazukhiro

Jamamoto Minoru

Mjurai Masaaki

Inaba Takaaki

Isizaka Noriko

Dates

2012-12-27—Published

2008-01-15—Filed