FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology and can be used for enantioselective enzymatic restoration of keto compound of general formula (I):
,
where R represents a protecting group for the functional amino groups, and X is -Cl, -CN, -OH, Br, F. The polypeptides which have oxyreductive activity, depending on the amino acid sequence restore the said compound to the corresponding R,S- and S,S-hydroxy compounds.
EFFECT: use of the invention enables to reduce the ability to form the by-products in restoration of keto compound of the formula.
6 cl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PRODUCING (R)-1-ARYL-2-TETRAZOLYLETHYL ETHER OF CARBAMIC ACID | 2010 |
|
RU2539983C2 |
| OBTAINING XYLITOL FROM GLUCOSE BY MEANS OF A RECOMBINANT STRAIN | 2015 |
|
RU2693593C2 |
| CHEMICAL PROCESS FOR PREPARING SPIROINDOLONES AND INTERMEDIATES THEREOF | 2013 |
|
RU2662815C2 |
| MODIFIED MICROORGANISMS AND METHODS FOR BUTADIENE PRODUCTION WITH THEIR USE | 2012 |
|
RU2639564C2 |
| METHOD FOR PRODUCTION OF CHIRAL ALPHA-HALOALKANOIC ACIDS | 2018 |
|
RU2790496C2 |
| IMMUNOGENIC HYBRID POLYPEPTIDES AGAINST OBESITY AND COMPOSITION OF ANTI-OBESITY VACCINES, CONTAINING SAID POLYPEPTIDES | 2007 |
|
RU2418005C2 |
| PRODUCING TERMINAL ALKENES VIA ENZYMATIC DECARBOXYLATION OF 3-HYDROXYALKANOIC ACIDS | 2009 |
|
RU2571933C2 |
| GLYCOLIPID ACYLTRANSFERASE VERSIONS, SYNTHESIS METHOD THEREOF AND USE | 2004 |
|
RU2377300C2 |
| PROTEINS | 2004 |
|
RU2518345C2 |
| METHODS FOR ENHANCING THE DEGRADATION OR CONVERSION OF CELLULOSIC MATERIAL | 2006 |
|
RU2441912C2 |
