SALTS OF 4-[2-[[5-METHYL-1-(2-NAPHTHALINYL)-1H-PYRAZOL-3-YL]OXY]ETHYL]MORPHOLINE Russian patent published in 2015 - IPC C07D413/12 C07D403/12 A61K31/4155 A61K31/5375 A61P25/28 

Abstract RU 2559325 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed invention relates to field of organic chemistry, namely to hydrochloride salt of 4-[2-[[5-methyl-1-(2-naphthalinyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine. Invention also relates to method of obtaining said hydrochloride salt, pharmaceutical composition, based on said hydrochloride salt, application of said hydrochloride salt.

EFFECT: novel hydrochloride salt of 4-[2-[[5-methyl-1-(2-naphthalinyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine useful at treatment and/or prevention of diseases, associated with sigma receptor, is obtained.

6 cl, 30 dwg, 11 tbl, 9 ex

Similar patents RU2559325C2

Title Year Author Number
4-[2-[[5-METHYL-1-(2-NAPHTHALINYL)-1H-PYRAZOL-3-YL]OXY]ETHYL]MORPHOLINE HYDROCHLORIDE POLYMORPH AND SOLVATES 2011
  • Berenger Majmo Ramon
  • Medrano Ruperes Khorkhe
  • Benet Bukhkhol'Ts Khordi
  • Puig Fernandes Laura
  • Pellekha Pukseu Laja
RU2560150C2
METHOD OF PRODUCING NAPHTHALEN-2-YL-PYRAZOL-3-ONE INTERMEDIATE COMPOUNDS USED IN SYNTHESIS OF SIGMA RECEPTOR INHIBITORS 2009
  • Torrens Khover Antoni
  • Korbera Arkhona Khordi
  • Kuberes-Altisent Marija Rosa
RU2509763C2
SIGMA-RECEPTOR INHIBITORS 2005
  • Laggner Kristian
  • Kuberes-Altisent Marija Rosa
  • Kholents Jorg
  • Berrokal'-Romero Khuana Marija
  • Kontikhoch-L'Obet Marija Montserrat
RU2417987C2
PYRAZOLE COMPOUNDS AS SIGMA RECEPTOR INHIBITORS 2011
  • Garsija Lopes Monika
  • Torrens Khover Antoni
  • Dias Fernandes Khose Luis
  • Kaamano Moure Ana Marija
RU2582338C2
SALTS OF 1-(4-(2-((1-(3,4-DIFLUOROPHENYL)-1N-PYRAZOL-3-YL)METHOXY)ETHYL)PIPERAZIN-1-YL)ETHANONE 2016
  • Torrens-Jover Antoni
  • Almansa Rosales Carmen
RU2727974C2
USE OF SIGMA LIGANDS IN DIABETES TYPE-2 ASSOCIATED PAIN 2012
  • Vela Ernandes Khose Migel
  • Martin Fonteles Mariya Isabel
RU2608943C2
SIGMA-RECEPTOR INHIBITORS 2005
  • Korbera Arkhona Khordi
  • Kuberes-Altisent Marija Rosa
  • Kholents Jorg
  • Martines-Ol'Mo Daniehl'
  • Van'O-Domenech David
RU2404972C2
2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5-HT3 MODULATORS 2007
  • Fehjrfaks Dehvid Dzh.
  • Jan Chzhitsaj
RU2448105C2
CRYSTALLINE FORMS OF FREE BASE 2014
  • Abe Takasi
  • Bakton Grekhem
  • Devis Robert
  • Khuper Mark
  • Li Pen
  • Maruyama Khideaki
  • Takasuga Masakhiro
  • Uennogl Lourens P.
  • Yamamoto Yukhei
  • Yamasita Khironori
RU2675851C2
SUBSTITUTED PYRAZOLES, PHARMACEUTICAL COMPOSITION BASED ON SAID, METHOD OF PATIENT TREATMENT, INTERMEDIATE COMPOUND 1993
  • Dzhen M.Brajt
  • Uillard M.Uehlch
RU2130453C1

RU 2 559 325 C2

Authors

Kuberes-Altisent Marija Rosa

Sola-Karandel' L'Juis

Garsija-Kousejro Urko

Dates

2015-08-10Published

2010-11-25Filed