MICROELECTRONIC SENSOR DEVICE FOR DETECTING LABEL PARTICLES Russian patent published in 2013 - IPC G01N21/55 G01N21/64 G01N33/543 

FIELD: chemistry.

SUBSTANCE: microelectronic sensor device for detecting target components containing label particles (1) includes: carrier (11) having a sample chamber (2) with a transparent wall observation, having on its inner side a binding surface (12) on which target components can collect, and on its outer side an optical structure; a light source (21) for emitting an input light beam (L1) into the carrier so that the light beam undergoes total internal reflection in the analysed region (13) on the binding surface; a light detector (31) for determining the amount of light in the output light beam (L2), having at least a certain portion of light that has undergone total internal reflection. The group of inventions also relates to a sample analysis carrier (11, 111, 211, 311, 411, 511) for the microelectronic sensor device in claim 1, a plate with cavities, having a plurality of said carriers and a method of detecting target components containing label particles (1) using said device by associating the amount of light in the input light beam (L1) with the measured amount of light in the output light beam (L2).

EFFECT: high sensitivity and accuracy of analysis.

14 cl, 18 dwg