METHOD OF TREATING EXPERIMENTAL MALLEUS Russian patent published in 2013 - IPC A61K31/43 A61P31/04 

Abstract RU 2490013 C1

FIELD: medicine.

SUBSTANCE: invention refers to microbiology and veterinary science and aims at treating experimental malleus. Golden hamsters that are animals highly malleus-sensitive, are infected with B.mallei c 5 in dose 104 microbial cells that corresponds to 103 Dim. The treatment starts either 4 hours later and represents an emergency prevention, or 24 h and 48 h later. An antibacterial agent is presented by meropenem in the liposomal form 15 mg in 0.5 ml, in dose 50 mg/kg/day; the preparation is administered intraperitoneally 5 times every 72 hours.

EFFECT: using the method improves the survival rates in animals suffering acute malleus.

2 cl, 2 ex, 2 tbl

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RU 2 490 013 C1

Authors

Iljukhin Vladimir Ivanovich

Rotov Konstantin Aleksandrovich

Senina Tat'Jana Vasil'Evna

Snatenkov Evgenij Aleksandrovich

Tikhonov Sergej Nikolaevich

Plekhanova Natal'Ja Gennad'Evna

Kulikova Anastasija Stanislavovna

Shubnikova Elena Vladimirovna

Dates

2013-08-20Published

2012-07-06Filed