FIELD: medicine.
SUBSTANCE: invention refers to microbiology and veterinary science and aims at treating experimental malleus. Golden hamsters that are animals highly malleus-sensitive, are infected with B.mallei c 5 in dose 104 microbial cells that corresponds to 103 Dim. The treatment starts either 4 hours later and represents an emergency prevention, or 24 h and 48 h later. An antibacterial agent is presented by meropenem in the liposomal form 15 mg in 0.5 ml, in dose 50 mg/kg/day; the preparation is administered intraperitoneally 5 times every 72 hours.
EFFECT: using the method improves the survival rates in animals suffering acute malleus.
2 cl, 2 ex, 2 tbl
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Authors
Dates
2013-08-20—Published
2012-07-06—Filed