COMPOSITION FOR REGULATION OF LIPASE-CATALISED REACTIONS Russian patent published in 2013 - IPC A61K9/10 A61K31/20 A61K31/201 A61K31/202 A61K31/22 A61K47/14 A61K47/44 A61P3/04 

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed is application of formulation, which includes lipophilic and hydrophilic phases in form of emulsion, which contains at least one SAS - mono- or diacylglyceride, in which Sn2 position is acylated, with inter-phase pressure in the range approximately 5-50 mN/m, for preparation of composition, intended for regulation of lipolysis by at least partial substitution of lipase substrates on surface of separation between lipophilic and hydrophilic phases, for prevention and treatment of metabolic malfunctions. Also claimed is composition for regulation of lipolysis, which includes at least one oil and is enriched with at least one SAS and hydrophilic phase in form of emulsion, in which SAS is mono- or diacylglyceride, in which Sn2 position is acylated, is not susceptible to cleavage by at least one lipase, and is present in weight ratio to at least one lipid, which constitutes from nearly 1:1000 to 100:1, and composition demonstrates value of inter-phase pressure about 5-50 mN/m. Invention can be applied for reduction of fat intake in food digestion, avoiding direct lipase inhibition.

EFFECT: invention makes it possible to exclude lipases from the surface of oil/water phase separation and in such way reduce their lipolytic activity.

13 cl, 10 dwg